537 Racial differences in pharmacologic treatment for newborns with neonatal opioid withdrawal syndrome

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Pharmacologic management of the opioid neonatal abstinence syndrome.

Opioid use in pregnant women has increased over the last decade. Following birth, infants with in utero exposure demonstrate signs and symptoms of withdrawal known as the neonatal abstinence syndrome (NAS). Infants express a spectrum of disease, with most requiring the administration of pharmacologic therapy to ensure proper growth and development. Treatment often involves prolonged hospitaliza...

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Buprenorphine for Medication-Assisted Treatment of Opioid Use Disorder in Pregnancy: Relationship to Neonatal Opioid Withdrawal Syndrome

Objective  To examine the relationship between antepartum buprenorphine dose for medication-assisted treatment (MAT) of opioid use disorder (OUD) and incident neonatal opioid withdrawal syndrome (NOWS). Study Design  We performed a prospective cohort study of pregnant women with a singleton gestation diagnosed with OUD and receiving buprenorphine for MAT at a tertiary care academic institution ...

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Neonatal Abstinence Syndrome (NAS; Neonatal Withdrawal) — Pathophysiology and Treatment

Neonatal abstinence syndrome is characterized by the onset of withdrawal symptoms in a neonate due to prenatal or postnatal exposure to illegal drugs or prescription drugs. The clinical presentation is usually dependent on the duration and time of exposure to the drug and not the drug itself. Meconium analysis or umbilical cord testing are the gold standard for the diagnosis of neonatal abstine...

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Editor’s Note: Adverse drug reactions experienced by UWMC or HMC patients and reported to the pharmacy are reviewed quarterly by the Pharmacy & Therapeutics Committee. Following the Committee’s review, a summary is published in this newsletter (see page 9) along with a companion article regarding some aspect of adverse drug reactions. It is hoped that these articles will be useful tools to remi...

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Four term neonates presented with symptoms such as jitteriness and necrotising enterocolitis after paroxetine exposure in utero.

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ژورنال

عنوان ژورنال: American Journal of Obstetrics and Gynecology

سال: 2021

ISSN: 0002-9378

DOI: 10.1016/j.ajog.2020.12.558